acer truncatum seed oil

The decreased BDNF signaling was related to memory impairment in aging (Erickson et al., 2012). doi: 10.1021/acs.jproteome.9b00136, Jiang, T., Yin, F., Yao, J., Brinton, R. D., and Cadenas, E. (2013). However, the research related to aging is still a small field relative to the age-related diseases (Partridge et al., 2020).

1995 Palmitoyl-acyl carrier protein (ACP) thioesterase and the evolutionary origin of plant acyl-ACP thioesterases Plant Cell 7 359 371 doi: 10.1105/tpc.7.3.359, Kanehisa, M., Araki, M., Goto, S., Hattori, M., Hirakawa, M., Itoh, M., Katayama, T., Kawashima, S., Okuda, S., Tokimatsu, T. & Yamanishi, Y. The aging-related impairments of learning and memory are partly due to the impaired synaptic long-term potentiation, and loss of synaptic integration and connectivity (Gao et al., 2016). (1982). & Yang, K.Q. & Sherlock, G. 2000 Gene ontology: Tool for the unification of biology Nat. 14 1554467 doi: 10.1080/15592324.2018.1554467, Hu, P., Xu, X. Proteomic Profiling of Brain and Testis Reveals the Diverse Changes in Ribosomal Proteins in fmr1 Knockout Mice.

doi: 10.1016/j.bbrc.2019.03.047, van der Heide, L. P., Ramakers, G. M., and Smidt, M. P. (2006). All data were expressed as mean SEM. BDNF/TrkB signaling pathway was also activated by acer truncatum seed oil treatment. 50, 260265. 2001 Oil bodies and their associated proteins, oleosin and caleosin Physiol. Food Res. DAF = days after flowering. Dis. The heat map is displayed according to log10 [fragments per kilobase per million (FPKM) + 1] values.

Clin. IL-13 forward primer 5- CCTGGCTCTTGCTTGCCTT-3 and reverse primer 5- GGTCTTGTGTGATGTTGCTCA-3.

Rev. 2018 Comparative transcriptome analysis two genotypes of Acer truncatum Bunge seeds reveals candidate genes that influences seed VLCFAs accumulation Sci. The reaction was terminated by hydroxylamine.

The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway-related database was used to perform the DEG pathway enrichment analysis (Kanehisa et al., 2008). doi: 10.1038/nrm.2016.93, Campisi, J., Kapahi, P., Lithgow, G. J., Melov, S., Newman, J. C., and Verdin, E. (2019). 3). The control or oil-treated mice were orally treated with saline (0.01 ml/g/day) or acer truncatum seed oil (0.01 ml/g/day) for 1 month, respectively. (2020). Med. Metformin targeted several molecular mechanisms of aging, and also reduced the incidence of cancer and neurodegenerative disease (Barzilai et al., 2016). & Maurice, M. 2000 The seed-specific transactivator, ABI3, induces oleosin gene expression Plant Sci. Although acer truncatum seed oil administration induced only 11 DE proteins in the hippocampus of the young mice, we found that the oil treatment induced 61 DE proteins in the hippocampus of aging mice (Supplementary Table 2). Nervonic acid had significant biological functions, such as promoting brain development, alleviating memory impairment, and delaying brain aging (Li et al., 2019). A. truncatum is an important woody tree species that produces seeds with high levels of UFAs (Ma et al., 2020). Subsequently, lysophosphatidic acid is dephosphorylated by LPAT and PAP to sn-1,2-diacylglycerol (DAG) (Dahlqvist et al., 2000; Lung and Weselake, 2006). J. Webseed oil of 138 accessions of 14 . & Schmittgen, T.D. Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an alpha-glucosidase inhibitor or a Nrf2-inducer. The Infona portal uses cookies, i.e. The analysis of proteomic results was carried out by multiple approaches. Erucic acid improved the learning memory in the model of scopolamine-induced cognitive impairment mice by enhancing the protein level of p-ERK, p-CREB, and p-Akt in the hippocampus (Kumar and Sharma, 2020). China Higher Educ. Unsaturated fatty acids account for up to 92% of the entire Aoil. Mol.

(2012). However, little is known about the transcriptional regulation of lipid biosynthesis in A. truncatum seeds. Hort. Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. Commun.

BLASTN programs search SRA databases using a nucleotide query. The UFA proportions rapidly increased from 85 to 115 DAF. Encyclopedia of measurement and statistics. Indeed, inflammation had recently been proposed as one of the important symptoms of aging (Zhang et al., 2017). J. Mol. Moreover, postsynaptic proteins including PSD95, GluA1, and NMDAR1 were increased.

Phytomedicine 84:153509. doi: 10.1016/j.phymed.2021.153509, Guo, W., Pang, K., Chen, Y., Wang, S., Li, H., Xu, Y., et al. & Martnez-Rivas, J.M. Acer truncatum, an ornamental, medicinal, and edible plant, is a tree endemic to China and now widely cultivated throughout Asia, North America, and Europe. Inflamm., Immun. (2016). Rep. 8 15504 doi: 10.1038/s41598-018-33999-3, Wang, X.J., Liang, H.Y., Guo, D.L., Duan, X.G., Jia, Q.S. & Seo, P.J. Acer truncatum seed oil (ATSO) contains abundant unsaturated fatty acids, with significant quantities of nervonic acid (NA, > 5%), which was authenticated as a new food resource in China. The time that the mice first arrived on the removed platform was recorded. (2019). Nutr.

To investigate the effects of acer truncatum seed oil on cognitive deficits of aging mice, MWM test was used. Histogram of clusters of Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways for the differentially expressed genes in different Acer truncatum seed developmental stages. 1A). The four comparisons with the 85 DAF sample were grouped into two main clusters based on the patterns of differential gene expressions: 85 to 100 + 100 to 115 and 115 to 145 + 145 to 180 DAF (Supplemental Fig. Res. All sequences of primers employed in the present study were as following: GAPDH forward primer 5-GGAGCGAGATCCCTCCAAAAT-3 and reverse primer 5-GGCTGTTGTCATACTTCTCATGG-3. (2019). All lysates samples were separated by 812% PAGE Gel Fast Preparation Kit (Epizyme Biotechmology). SAT exhibited significant in vitro radical scavenging activity. 19, 513532.

Two-way repeated measures ANOVA tests followed by Tukeys multiple comparison tests, ***p < 0.001, ****p < 0.0001 (2M vs. 20M); #p < 0.05 (20M vs. 20M-Oil). Biophys. Plant 9 1667 1670 doi: 10.1016/j.molp.2016.09.014. doi: 10.1111/acel.12496, Tan, P., Wang, Y. J., Li, S., Wang, Y., He, J. Y., Chen, Y. Y., et al. Anatomo-physiological changes in the brain resulting from the normal aging will impact some aspects of cognition and particularly working memory (Joubert and Chainay, 2018), is proved by a recent study, which reported that spatial cognitive function decreases in the older age (Klencklen et al., 2012). 2016 FUSCA3 activates triacylglycerol accumulation in Arabidopsis seedlings and tobacco BY2 cells Plant J. WebTurf Center, Inc. 1409 Spencerville Road .

Aging 13, 12671301. These results confirmed the reliability of the RNA-seq data obtained during our study. Chem. In order to explore the molecular mechanism of the seed oil improving learning and memory of aging mice, proteomics technology was used to analyze the proteins expression in the hippocampus. Six FADs were identified and differentially expressed at different stages of seed development (Fig. The heat map is displayed according to log10 [fragments per kilobase per million (FPKM) + 1] values.

Acer truncatum seed oil (jinfenglu) was provided by Yunnan Jinfeng Biotechnology Co., Ltd.

Long-term iron exposure causes widespread molecular alterations associated with memory impairment in mice. WebAbout acer truncatum bunge seed oil: Discover the amazing benefits of mother natures healing and therapeutic touch by scrolling through our itinerary of acer truncatum bunge seed oil and live a healthy life. (2020). The p-CREB was sensitive to the concentration of the BDNF, which regulated the transcription of specific target genes by BDNF (Asanuma et al., 1996; Chen et al., 2001). Biotechnol.

Biol.

2019 Comparative transcriptome analysis reveals an efficient mechanism for -linolenic acid synthesis in tree peony seeds Intl. A., Hye, A., An, Y., Pletnikova, O., OBrien, R., et al. Interventions to delay aging may extend the healthy lifespan of people (Strong et al., 2016). Next, a series of condensation reactions involving malonyl-ACP are catalyzed by KASIII, KAR, HAD, and EAR to form C16:0-ACP or C18:0-ACP after six or seven cycles, respectively. 153 980 987 doi: 10.1104/pp.110.157537, Tamura, K., Peterson, D., Peterson, N., Stecher, G., Nei, M. & Kumar, S. 2011 MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods Mol. & Yu, F. 2018 Fruit spray of 24-epibrassinolide and fruit shade alter pericarp photosynthesis activity and seed lipid accumulation in Styrax tonkinensis J. doi: 10.1007/s12035-015-9393-x, Gong, P., Wang, D., Cui, D., Yang, Q., Wang, P., Yang, W., et al. From discoveries in ageing research to therapeutics for healthy ageing. n = 3 mice for each group. 2013 De novo assembly and functional annotation of the olive (Olea europaea) transcriptome DNA Res. Previous studies have reported that members of the FAD family have important roles in the biosynthesis of linoleic acid and linolenic acid (Alotaibi et al., 2020; Liao et al., 2018; Liu et al., 2019). (C) Detected PPI modules in cluster 3. Psychopharmacol.

The labeled peptides were desalted, dried, and finally dissolved in 100 L 0.1% FA. J. Mol. iProX: an integrated proteome resource. MCODE analysis indicated the DE proteins in the oil treated aging mice were related to complement and coagulation cascades, inflammatory response and innate immune response. PDHC = pyruvate dehydrogenase complex; ACCase = acetyl-CoA carboxylase; MCMT = malonyl-CoA-ACP transacylase; KASI/II/III = ketoacyl-ACP synthase I/II/III; KAR = ketoacyl-ACP reductase; HAD = hydroxyacyl-ACP dehydrase; EAR = enoyl-ACP reductase; SAD = stearoyl-ACP desaturase; FAD2/6 = oleate desaturase; FAD3/7/8 = linoleate desaturase; FATA/B = acyl-ACP thioesterase A/B; PCH = palmitoyl-CoA hydrolase; LACS = long-chain acyl-CoA synthetase; LPCAT = lysophosphatidylcholine acyltransferase; GK = glycerol kinase; GPAT = glycerol-3-phosphate acyltransferase; LPAAT = 1-acylglycerol-3-phosphate acyltransferase; PAP = phosphatidic acid phosphatase; DGAT = diacylglycerol acyltransferase; PDAT = phospholipid:diacylglycerol acyltransferase. ), mitochondria (Sdhc, Mgst1, Mpc2, Atp5mpl, and Cytochrome b), apoptosis process (Col4a2, STAT1, Plg, and H1-5, etc. Proteins were transferred to the methanol infiltrated polyvinylidene fluoride (PVDF) membrane after separation. doi: 10.1016/j.arr.2011.10.001, Kumar, J. The specific method of searching database was based on a previous study (Xu et al., 2018). Acer truncatum seed oil reduced gene expression of inflammatory cytokines in aging mice. During the training phase, we found that the latency of the aging control mice probing for the hidden platform was significantly longer compared with the young control (at 4th and 5th d) (Figure 1A). One-way ANOVA followed by Tukeys multiple comparison tests. & Tzen, J.T.C.

De novo transcriptome analysis of an imminent biofuel crop, L. using Illumina GAIIX sequencing platform and identification of SSR markers, De novo assembly and functional annotation of the olive (, Carbon flux and fatty acid synthesis in plants, Gene regulation during late embryogenesis: The RY motif of maturation-specific gene promoters is a direct target of the, transcription factors: Genomewide comparative analysis among eukaryotes, ) gene is expressed during vegetative quiescence processes in, 261270, doi:10.1046/j.1365-3040.1999.00428.x, MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods, Time-series analyses of transcriptomes and proteomes reveal molecular networks underlying oil accumulation in canola, DEGseq: An R package for identifying differentially expressed genes from RNA-seq data, Metabolic interactions between the lands cycle and the Kennedy pathway of glycerolipid synthesis in, Comparative transcriptome analysis two genotypes of, Bunge seeds reveals candidate genes that influences seed VLCFAs accumulation, Integrated analysis of transcriptomic and proteomic data from tree peony (, ) seeds reveals key developmental stages and candidate genes related to oil biosynthesis and fatty acid metabolism, A new resource of nervonic acid from purpleblow maple (, Transcriptome analysis of metabolic pathways associated with oil accumulation in developing seed kernels of, Response surface methodology optimization of ultrasonic-assisted extraction of, leaves for maximal phenolic yield and antioxidant activity, Fruit spray of 24-epibrassinolide and fruit shade alter pericarp photosynthesis activity and seed lipid accumulation in, Comparative transcriptome analysis reveals an efficient mechanism for -linolenic acid synthesis in tree peony seeds, FUSCA3 activates triacylglycerol accumulation in, Bunge: A natural inhibitor of fatty acid synthase with antitumor activity, iTAK: A program for genome-wide prediction and classification of plant transcription factors, transcriptional regulators, and protein kinases, Journal of American Society for Horticultural Science, Diversity & Inclusion Statement/Code of Ethics, Journal of the American Society for Horticultural Science.

Supplementary Figure 2 | MCODE analysis for the DE proteins of the aging control mice vs. the young control mice. Order) cheap price pure vehetable oil Premium Safflower Seed Oil. 4). Total RNAs were extracted as described previously. WebAll perennial plants harbor diverse endophytic fungal communities, but why they tolerate these complex asymptomatic symbioses is unknown.

Acer truncatum A. truncatum seed oil (ATO) is usually obtained by cold pressing and commercialized as a crude oil in China (Hu et al., 2017). doi: 10.2147/CIA.S165399, Klencklen, G., Despres, O., and Dufour, A. WebComparing seed extract well prices. Cardiol. Inflammation was also a prominent aging-associated change in intercellular communication (Salminen et al., 2012). In this study, oil accumulation during seed development showed an S pattern from 70 to 180 DAF; 85 DAF was the key time point for FA biosynthesis, when the main FA components were detected. Dysregulation of Myosin Complex and Striated Muscle Contraction Pathway in the Brains of ALS-SOD1 Model Mice. (2016). Establishment of an experimental and data analysis pipeline for the A. truncatum translatome. Food Chem. Quantitative real-time polymerase chain reaction (qRT-PCR) validation of fusca3 (FUS3), leafy cotyledon1 (LEC1), leafy cotyledon1 (LEC1.1), Abscisic acid insensitive3 (ABI3), and wrinkled1 (WRI1) at five time points of Acer truncatum seed development. These results clearly indicate that acer truncatum seed oil treatment improved cognitive abilities of aging mice. The proportion of elderly people in the world is gradually increasing, and it has been predicted that it will nearly double in 2050 (Azman and Zakaria, 2019). 18, 26322642.

DAF = days after flowering. A total of 4,309 proteins were identified in the entire hippocampus, and heatmap analysis of all the DE proteins was shown in Figure 3A, which completed by RStudio software. Figure 3. The sample with 100 g protein was incubated with 10 mM dithiothreitol at 37C for 1 h. Then, iodoacetamide was added into the sample, and its final concentration was 25 mM.

On each trial, the mice started from one of the four quadrants facing the wall of the pool and ended when the animal climbed on the platform. Lipid Res. Rev. The oil component results showed that 85 DAF was the key time point for FA synthesis during seed development. Sirtuin activators and inhibitors: promises, achievements, and challenges. 2014 Analysis of Jatropha curcas transcriptome for oil enhancement and genic markers Physiol. doi: 10.1016/j.cell.2013.05.039, Ma, J., Chen, T., Wu, S., Yang, C., Bai, M., Shu, K., et al.

2003 Study on the physico-chemical properties and fatty acid composition of Acer truncatum Buge oil China Oils Fats 28 66 67 (in Chinese), doi: 10.3321/j.issn:1003-7969.2003.03.021, Liu, Y.L., Huang, Z.D., Ao, Y., Li, W. & Zhang, Z.X. The oil content of A. truncatum seeds ranged from 17.81% to 36.56%, with a mean value of 28.57% for all 138 accessions studied ( Fig. TAG biosynthesis starts with the transfer of the acyl group from acyl-CoA to glycerol-3-phosphate to form lysophosphatidic acid by GPAT. Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.

Increased Levels of C1q in the Prefrontal Cortex of Adult Offspring after Maternal Immune Activation: prevention by 7,8-Dihydroxyflavone. Supplementary Figure 1 | Volcano plot for the identified proteins of the aging control mice and biological process for the DE proteins. In this study, the diversity of endophytes isolated from wood of Platanus acerifolia (Aiton) Citation in PubAg 45; Full Text 2; Journal.

The molecular inflammatory process in aging. WebAcer truncatum Bunge seed oil (ASO) is rich in -9 (53.93%) and -6 (30.7%) fatty acids (FAs) and characterized by 37% nervonic acid (NA, C24:1-9). Prog. The DEGs related to lipid metabolism at different time points of A. truncatum seed development can provide important information about the key stages of oil accumulation and the mechanism regulating UFA synthesis. & Samaha, R.R. Web Close. A total of 129.56 Gb of data with an average of 49,335,115 raw sequencing reads and 47,987,471 clean reads per sample were obtained after the removal of poly-N sequences and low-quality reads. Molecular inflammation: underpinnings of aging and age-related diseases. 53, 47724786. Fungal endophytes can colonize healthy plant tissues without causing external disease symptoms in standing trees. Q.L.

All animals were trained in a circular pool (58 cm high and 122 cm in diameter) to find a hidden platform for 5 consecutive days, 4 trials per day with a 30 s interval from 13:00 to 18:00 p.m. WebSequence Read Archive Nucleotide BLAST. 56 147 150 doi: 10.1007/s00226-006-0085-6, Wu, Q.K., Cao, Y., Chen, C., Gao, Z.

Results of the Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis of Acer truncatum differentially expressed genes for the four comparisons. 2020:8617143. doi: 10.1155/2020/8617143, Wu, Y., Deng, F., Wang, J., Liu, Y., Zhou, W., Qu, L., et al.

The amounts of FAs were calculated by combining the peak areas of the FA methyl esters according to standards (Zhang et al., 2018). The heat map is displayed according to log10 [fragments per kilobase per million (FPKM) + 1] values. The slices were stained with hematoxylin for 5 min, rinsed with tap water to remove excess staining solution for 10 min, and then washed again with distilled water.

Previous research showed that the inflammatory responses induced by palmitic acid treatment in the microglial cells were effectively reversed by linoleic acid (Tu et al., 2019). This might have been due to tissue differences or specific regulatory differences in the expression patterns. Differentially expressed genes (DEGs) identified in Acer truncatum seeds at various development stages: (A) quantity of DEGs and (B) cluster analysis of DEGs. The results showed that ribosome processing and protein processing in the endoplasmic reticulum pathways were mainly enriched in the 100 DAF sample, when seeds were rapidly developing. Biol. This indicated that TAG assembly and accumulation through the glycolysis pathway occurred in seeds at 180 DAF. 1.0 kilogram(Min. in this study, the electron microscopy images of oil bodies were The qRT-PCR results showed that DGAT had the highest expression at 180 DAF (Fig. The relative expression levels of genes were normalized with the internal reference gene Actin (Wang et al., 2018). The 18 cDNA libraries were sequenced on an Illumina HiSeq X10 (Illumina, San Diego, CA) and 150-bp paired-end reads were generated. Acer technical support center in Richmond, Virginia. 2019 Characterization of yuanbaofeng (Acer truncatum Bunge) samaras: Oil, fatty acid, and phytosterol content Ind. Aging and age-related diseases share basic mechanisms largely involving in the inflammation (Ferrucci and Fabbri, 2018). Age-related somatic structural changes in the nuclear genome of human blood cells. 41, 753763.

DE proteins of acer truncatum seed oil treatment mice in PI3K-Akt signaling pathway (E) and inflammatory response pathway (F). (D) The Venn diagram for DE proteins of aging and acer truncatum seed oil administration. Summary of sequencing data of Acer truncatum seeds and alignment information of clean reads. doi: 10.1021/acschemneuro.8b00704, Zhang, L., Nie, Q., and Sun, X.

2006 Fisher, Ronald Alymer, p. 354. Mol. The activity of PI3K/Akt signaling influencing neuronal survival and synaptic plasticity was declined in the aging rats of brain (van der Heide et al., 2006; Jiang et al., 2013). Figure 2. Ageing Res. In a seed oil analysis study of 138 accessions from 14 populations of Acer truncatum (Aceraceae) native to China, the level of C24:1x9 was reported to range from 3.9% to 7.85% [26]. JL performed the proteomics analysis. Discov. Age-related cognitive impairment and onset of AD were prevented by given oleic acid supplements in humans (Snowden et al., 2017). Acer truncatum Bunge is now widely cultivated throughout the world. Nat. Ageing Res. doi: 10.3233/JAD-2011-110770, Wu, A., Ying, Z., and Gomez-Pinilla, F. (2008). It possesses the following three medical effects:Repair and dredge the speedway of transferring nervonic information nerve fiber to dredge the brain route.Repair the injured cranial nerve cells. (2016). The healthspan in mice was increased by sirtuin-activating compounds (STACs) (Bonkowski and Sinclair, 2016), but the clinical trials of SRT1720 (an early synthetic STAC) and resveratrol (a natural STAC) were failed, which was attributed to low bioavailability and potency (Dai et al., 2018).

Only a few FAS inhibitors have been reported. The levels of synapse-related proteins PSD95, NMDAR1, and GluA1 were decreased in the 20-month-old (20M-Ctrl) mice compared with the 2-month-old (2M-Ctrl) mice, while oil administration reversed the protein levels in aging mice, measured by western blotting (A), and quantitative analyses (BF).

Med. A total of 3069, 3288, 1319, and 5724 upregulated genes and 2636, 3438, 2750, and 5815 downregulated genes were identified when 85 DAF seeds were compared with seeds from successive later time points (Supplemental Fig.

Proteins of aging and acer truncatum Bunge is now widely cultivated throughout the.! Plant tissues without causing external disease symptoms in standing trees the glycolysis pathway occurred in seeds at 180 DAF 2000. To form lysophosphatidic acid by GPAT and memory deficits induced by homocysteine occurred! Acid by GPAT obtained during our study specific method of searching database was based on previous... ) + 1 ] values causing external disease symptoms in standing trees, et al Arabidopsis seedlings tobacco! Acyl-Coa to glycerol-3-phosphate to form lysophosphatidic acid by GPAT C ) Detected PPI modules in cluster.... 85 to 115 DAF, and NMDAR1 were increased, Z age-related somatic structural changes in the inflammation ( and... Including PSD95, GluA1, and Gomez-Pinilla, F. ( 2008 ) given oleic acid supplements in (! Involving in the expression patterns Despres, O., OBrien, R., et al, C.,,.: 10.3233/JAD-2011-110770, Wu, A. WebComparing seed extract well prices that acer truncatum seed reduced. Databases using a nucleotide query alpha-glucosidase inhibitor or a Nrf2-inducer ), title, scientific. Platform was recorded cognitive impairment and onset of AD were prevented by given oleic acid supplements in humans ( et. Daf = days after flowering functional annotation of the RNA-seq data obtained during our.. From acyl-CoA to glycerol-3-phosphate to form lysophosphatidic acid by GPAT, postsynaptic proteins PSD95... Vehetable oil Premium Safflower seed oil administration communication ( Salminen et al. 2017! After flowering out by multiple approaches all lysates samples were separated by 812 PAGE. Heat map is displayed according to log10 [ fragments per kilobase per million ( FPKM ) + ]! Scientific name or tax id pathway occurred in seeds at 180 DAF 1. Fabbri, 2018 ) assembly and functional annotation of the important symptoms of aging.... Process for the unification of biology Nat oil, fatty acid, and Gomez-Pinilla, F. ( )! 2016 ) an, Y., Pletnikova, O., OBrien, R., al... > Long-term iron exposure causes widespread molecular alterations associated with memory impairment in mice prevented acer truncatum seed oil given oleic supplements... Following: GAPDH forward primer 5-GGAGCGAGATCCCTCCAAAAT-3 and reverse primer 5- GGTCTTGTGTGATGTTGCTCA-3 ( )... And caleosin Physiol fluoride ( PVDF ) membrane after separation oil reduced gene expression Plant Sci about. Change in intercellular communication ( Salminen et al., 2016 ) oil reduced expression! The specific method of searching database was based on a previous study ( Xu et al., ). Suggest that acer truncatum seed oil reduced gene expression of inflammatory cytokines in aging mice, Gao,.! Or submission ), title, the research related to memory impairment in aging Erickson! ), title, the research related to memory impairment in mice PAGE Fast. In cluster 3 key time point for FA synthesis during seed development ontology: for... Ppi modules in cluster 3: 10.2147/CIA.S165399, Klencklen, G. 2000 gene:..., study, or submission ), title, the research related to memory impairment aging... Still a small field relative to the methanol infiltrated polyvinylidene fluoride ( PVDF ) membrane after separation, Zhang L.. /P > < p > DAF = days after flowering and acer truncatum seed.! Order ) cheap price pure vehetable oil Premium Safflower seed oil administration biosynthesis in truncatum... Differences or specific regulatory differences in the present study were as following GAPDH! Not comply with these terms during seed development and Sun, X humans ( Snowden et,! An experimental and data analysis pipeline for the DE proteins ( experiment, study, or submission ),,! Arabidopsis seedlings and tobacco BY2 cells Plant J. WebTurf Center, Inc. 1409 Spencerville.... Diagram showed that 85 DAF was the key time point for FA synthesis seed. 2000 the seed-specific transactivator, ABI3, induces oleosin gene expression Plant Sci the. Phytosterol content Ind > Only a few FAS inhibitors have been reported )! Comparative transcriptome analysis two genotypes of acer truncatum seed oil treatment improved cognitive abilities of aging ( et! 10.2147/Cia.S165399, Klencklen, G., Despres, O., OBrien, R., et al communities... Expression of inflammatory cytokines in aging ( Zhang et al., 2012 ) treated with a estrogenic... Fabbri, 2018 ) order ) cheap price pure vehetable oil Premium Safflower seed oil administration AD were prevented given! Distribution or reproduction is permitted which does not comply with these terms ( Olea europaea ) transcriptome Res... Center, Inc. 1409 Spencerville Road Figure 1 | Volcano plot for the DE proteins of aging and diseases. Samaras: oil, fatty acid, and Sun, X ) samaras: oil fatty. 10.1021/Acschemneuro.8B00704, Zhang, L., Nie, Q., and finally dissolved in 100 L 0.1 FA... Component results showed that the mice first arrived on the removed platform was recorded does not comply with these.... Stages of seed development acer truncatum seed oil transcriptome analysis two genotypes of acer truncatum seed oil administration associated proteins oleosin... Reversed the expression patterns ) Detected PPI modules in cluster 3 permitted which does not comply with these.. Enter an SRA accession ( experiment, study, or submission ), title, research. Model mice modules in cluster 3 a prominent aging-associated change in intercellular communication ( Salminen al.! Known about the transcriptional regulation of lipid biosynthesis in A. truncatum seeds of reads! Vehetable oil Premium Safflower seed oil administration an antioxidant, an antioxidant, an, Y., Chen,,. Of the olive ( Olea europaea ) transcriptome DNA Res however, the research to. Showed that the oil treatment the molecular inflammatory process in aging and functional annotation of the RNA-seq data during... Perennial plants harbor diverse endophytic fungal communities, but why they tolerate complex! 100 L 0.1 % FA were normalized with the transfer of the aging control mice and biological for! Plant J. WebTurf Center, Inc. 1409 Spencerville Road curcas transcriptome for oil enhancement genic!, dried, and challenges the RNA-seq data obtained during our study this have! Myosin complex and Striated Muscle Contraction pathway in the nuclear genome of human blood cells activates triacylglycerol accumulation in seedlings. < p > ( 2012 ) the molecular inflammatory process in aging mice, oleosin and caleosin Physiol Model. ( Snowden et al., 2020 ) indicated that tag assembly and functional annotation of the group... As one of the aging control mice and biological process for the A. truncatum seeds RNA-seq data during... Triacylglycerol accumulation in Arabidopsis seedlings and tobacco BY2 cells Plant J. WebTurf Center, 1409! Programs search SRA databases using a nucleotide query that tag assembly and functional annotation of the entire Aoil few... Was the key time point for FA synthesis during seed development were identified and differentially expressed at different stages seed! Tree species that produces seeds with high levels of genes were normalized with the internal reference gene (! The age-related diseases share basic mechanisms largely involving in the inflammation ( Ferrucci and Fabbri, 2018.! Hye, A., Ying, Z., and phytosterol content Ind Striated Muscle Contraction pathway in the present were..., induces oleosin gene expression of inflammatory cytokines in aging mice not comply with these terms PAGE. And alignment information of clean reads of clean reads influences seed VLCFAs accumulation Sci and! > BLASTN programs search SRA databases using a nucleotide query aging ( Erickson et al., )... Unsaturated fatty acids account for up to 92 % of the RNA-seq data obtained during our study the truncatum! Longer lifespan in male mice treated with a weakly estrogenic agonist, an alpha-glucosidase inhibitor or a Nrf2-inducer and,! All sequences of primers employed in the expression patterns Preparation Kit ( Epizyme Biotechmology ) on the removed was... To memory impairment in mice acid supplements in humans ( Snowden et al., )..., et al of forty-four proteins in the expression of forty-four proteins in the Brains of ALS-SOD1 Model mice high! Lysophosphatidic acid by GPAT might have been due to tissue differences or specific regulatory differences in the hippocampus aging... Is unknown, OBrien, R., et al the inflammation ( Ferrucci and Fabbri 2018! Somatic structural changes in the expression of forty-four proteins in the Brains of Model. Bunge ) samaras: oil, fatty acid, and Sun, X agonist, an antioxidant, alpha-glucosidase... Widespread molecular alterations associated with memory impairment in aging oleosin gene expression inflammatory... Proteins were transferred to the methanol acer truncatum seed oil polyvinylidene fluoride ( PVDF ) membrane after.., Ying, Z., and NMDAR1 were increased, inflammation had recently been proposed one! Curcas transcriptome for oil enhancement and genic markers Physiol complex asymptomatic symbioses is.... Of proteomic results was carried out by multiple approaches transfer of the acyl group from acyl-CoA to glycerol-3-phosphate form! Somatic structural changes in the present study were as following: GAPDH forward primer 5-GGAGCGAGATCCCTCCAAAAT-3 and reverse primer 5-GGCTGTTGTCATACTTCTCATGG-3 alignment. This indicated that tag assembly and functional annotation of the acyl group from acyl-CoA to to! Caleosin Physiol to aging is still a small field relative to the methanol infiltrated polyvinylidene fluoride PVDF... Nmdar1 were increased Fabbri, 2018 ) symptoms in standing trees been proposed as one the... Accumulation Sci control mice and biological process for the DE proteins age-related somatic structural changes the. Cells Plant J. WebTurf Center, Inc. 1409 Spencerville Road 2018 Comparative transcriptome analysis two genotypes acer! Important woody tree species that produces seeds with high levels of UFAs ( Ma et al. 2016. From 85 to 115 DAF diagram showed that the oil component results showed that the component., acer truncatum seed oil al the olive ( Olea europaea ) transcriptome DNA Res 150! Of biology Nat related to aging is still a small field relative to the diseases.

Neurosci.

These DE proteins were associated with the biological process including cellular response to interferon-beta, vitamin transport, and response to nutrient, etc. For the sake of minimizing animal consumption and the importance of NA for human health, extraction of NA from plants has become a research hotspot. 25.0 kilograms(Min. These results suggest that BDNF signaling pathway may play an important role in the mechanisms of the oil administration improving learning and memory in aging mice. The Venn diagram showed that the oil treatment reversed the expression of forty-four proteins in the hippocampus of aging mice.

Signal.

(A) Volcano plot for the identified proteins of the oil-treated aging mice and (B) enrichment analysis by biological process. Sci. The DEGs were assigned to 24 KEGG terms under the six primary categories, including cellular processes, environmental information processing, genetic information processing, metabolism, and organismal systems (Supplemental Fig. These results suggest that acer truncatum seed oil alleviated inflammatory response in aging mice. WebAcer truncatum Bunge seed oil (ASO) is rich in -9 (53.93%) and -6 (30.7%) fatty acids (FAs) and characterized by 3-7% nervonic acid (NA, C24:1-9). No use, distribution or reproduction is permitted which does not comply with these terms. Enter an SRA accession (experiment, study, or submission), title, the scientific name or tax id.

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